Drug eruption
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እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
Drug eruption ሙሉ ሰውነቱን በመንካት ይገለጻል።
relevance score : -100.0%
Referencesየመድሃኒት ፍንዳታ በመባል የሚታወቁት በመድሀኒት የሚከሰቱ የቆዳ ምላሾች አንዳንድ ጊዜ ከባድ ሊሆኑ ይችላሉ። እነዚህ severe cutaneous adverse drug reactions (SCARs) የሚባሉት ከባድ ምላሾች ለሕይወት አስጊ እንደሆኑ ይቆጠራሉ። Stevens‑Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) እና drug reaction with eosinophilia and systemic symptoms (DRESS) ያሉ ሁኔታዎችን ያካትታሉ። SCARs አልፎ አልፎ ቢሆንም፣ በሆስፒታል ውስጥ የሚገኙ ታካሚዎች 2% ያጋጥማሉ።
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
31 ዓመቱ ያለች ሴት በቀኝ እግር አናት ላይ ህመም የሌለባት ቀይ ሽፋን ይዞ የቆዳ ህክምና ክፍልን ጎበኘች። picosecond laser ህክምናን ተከትሎ፣ ከአንድ ቀን በፊት doxycycline (100 mg) ወስደች። ባለፈው አመት፣ ተመሳሳይ doxycycline የድህረ-ሌዘር ሕክምናን ከወሰደች በኋላ በተመሳሳይ ቦታ ላይ ተመሳሳይ ችግር አጋጥሟታል። እሷ ምንም ታሪክ የለውም፣ እንደ ትኩሳት፣ በአካባቢው ወይም በሰውነቷ ውስጥ ሌሎች ምልክቶች የለውም።
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens‑Johnson syndrome (SJS) እና toxic epidermal necrolysis (TEN) እንደ erythema multiforme major እና staphylococcal scalded skin syndrome እና የመድኃኒት ምላሾች ካሉ የቆዳ በሽታዎች ውስጥ የሚለዩ ሁለት ከባድ የቆዳ ምላሽ ዓይነቶች ናቸው። SJS/TEN ብዙ ጊዜ የስርዓተ‑ምልክት ምልክቶች ያለው እና በቆዳ እና mucous membrane ላይ ጉዳት የሚያስከትል ብርቅ እና ከባድ ምላሽ ነው። ከ 80% በላይ የተጎዳቸው ጉዳዮች ላይ መድሃኒቶች እንደ ምንም አይነት መንስኤ ይሆናሉ።
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
የመድሃኒት ፍንዳታዎች በዋነኛነት በሕክምና ታሪክ እና በክሊኒካዊ ምርመራ ይመረመራሉ. የቆዳ ባዮፕሲ፣ የደም ምርመራዎች ወይም የበሽታ መከላከያ ምርመራዎችም ጠቃሚ ሊሆኑ ይችላሉ።
ፍንዳታውን የሚያስከትሉ የተለመዱ መድኃኒቶች ምሳሌዎች አንቲባዮቲክስ እና ሌሎች ፀረ-ተሕዋስያን መድኃኒቶች, ሰልፋ መድኃኒቶች, ስቴሮይድ ያልሆኑ ፀረ-ብግነት መድኃኒቶች (NSAIDs), የኬሞቴራፒ ወኪሎች ለአደገኛ በሽታዎች, ፀረ-ቁስሎች እና ሳይኮትሮፒክ መድኃኒቶች ናቸው።
○ ምርመራ እና ህክምና
ትኩሳት (የሰውነት ሙቀት መጨመር) ካለብዎት በተቻለ ፍጥነት የሕክምና እርዳታ ማግኘት አለብዎት. የተጠረጠረው መድሃኒት መቋረጥ አለበት (ለምሳሌ አንቲባዮቲክስ, ስቴሮይድ ያልሆኑ ፀረ-ብግነት መድኃኒቶች). ሆስፒታል ከመጎብኘትዎ በፊት እንደ ሴቲሪዚን ወይም ሎራታዲን ያሉ የአፍ ውስጥ ፀረ-ሂስታሚኖች ለማሳከክ እና ሽፍታ ሊረዱ ይችላሉ።
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
የደም ምርመራ (CBC, LFT, eosinophil ቆጠራ)
የአፍ ውስጥ ስቴሮይድ እና ፀረ-ሂስታሚን መድኃኒቶች በሐኪም ማዘዣ